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Ngày xuất bản: 02/12/2023
Số lượt xem tóm tắt: 59
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DOI: https://doi.org/10.51298/vmj.v532i2.7415
Số xuất bản
Tập 532 Số 2 (2023): Vietnam Medical Journal
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Le , N. V., Nguyen , M. A., & Dang , T. N. A. (2023). LONG TERM OUTCOME OF LAPAROSCOPIC RADICAL NEPHRECTOMY FOR PATHOLOGICAL T1, T2 RENAL CELL CANCER AT VIET DUC HOSPITAL. Tạp Chí Y học Việt Nam, 532(2). https://doi.org/10.51298/vmj.v532i2.7415

LONG TERM OUTCOME OF LAPAROSCOPIC RADICAL NEPHRECTOMY FOR PATHOLOGICAL T1, T2 RENAL CELL CANCER AT VIET DUC HOSPITAL

Le Nguyen Vu1,2,, Nguyen Minh An3, Dang Thi Ngoc Anh4
1 Viet Duc University Hospital
2 Vietnam National University
3 Saint Paul General Hospital
4 Vin Mec Times city Hospital

Nội dung chính của bài viết

Tóm tắt

Background: To evaluation of the long term outcome of laparoscopic radical nephrectomy for pathological T1, T2 renal cell cancer at Viet Duc Hospital. Methods: We retrospectively identified 73 patients who underwent RN between 2015 and 2022. We divided patients into three groups based on tumour size: <4 cm, 4– 7 cm, >7 cm. Clinical and paraclinical characteristics include age, gender, back pain, tumor size, tumor location, disease stage on computed tomography scans, histopathological results, postoperative outcomes and complications, postoperative survival time, and accumulated survival time. Results: the average age was 53.52 ± 12.17 years.  CT scans classified renal cell carcinoma stages preoperatively according to IUAC 2009: 53.4% were stage T1a, 42.4% were stage T1b, 2.8% were stage T2a, and 1.4% were stage T2b, 2 patients experienced infection at the trocar site used for kidney extraction, 4 patients developed postoperative fever, and 1 patient had postoperative bleeding requiring a blood transfusion. One patient underwent emergency open surgery immediately after discharge due to bleeding through the drainage. The postoperative complication rate according to the Clavien-Dindo classification was 11% (8 patients). The results show that 63 patients are still alive, 5 patients have passed away due to the disease, and 5 patients have died from other causes such as traffic accidents, cardiovascular diseases, and cerebral vascular accidents. The average follow-up time is 46.7±26.5 months. The cumulative survival rates at 3, 4, 5, 6, and 7 years after radical nephrectomy for the treatment of renal cell carcinoma were 100%, 97.6%, 94.8%, 90.9%, and 83.3%, respectively. The average additional survival time after surgery was 84.11 ± 1.80 months. Conclusions:  Laparoscopic radical nephrectomy for early-stage renal cell carcinoma (T1 and T2) demonstrates high surgical safety and absolute efficacy in oncology.

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Từ khóa

Laparocospy radical nephrectomy, tumour size

Tài liệu tham khảo

1. Cicco, A., Salomon, L., Hoznek, A., Saint, F., Alame, W., Gasman, D., Antiphon, P., Chopin, D.K., and Abbou, C.C. (2001) Results of retroperitoneal laparoscopic radical nephrectomy. J. Endourol. 15, 355–9
2. Hwang Gyun Jeon, Seol Ho Choo, Hyun Hwan Sung, Byong Chang Jeong (2014) Small tumour size is associated with new-onset chronic kidney disease after radical nephrectomy in patients with renal cell carcinoma. European Journal of Cancer 50 (2014) 64–69 http://dx.doi.org/10.1016/j.ejca.2013.08.018
3. Nguyễn Minh Tuấn, Cao Văn Trí (2023). Evaluation of Treatment Outcomes for Renal Cell Carcinoma with Nephron-Sparing Surgery at Da Nang Hospital. Journal of medical Cần thơ, 5, 232- 235
4. Pyo P., et al (2008), “Retroperitoneal laparoscopic partial nephrectomy:
Surgical experience and outcome”, J Urol, 180, pp. 1279-1283.
5. Sobey S, et al (2012), Minimally invasive heminephrectomy feasibility
and outcomes, J Endo, 26(7). 866-870.
6. Ohno Y, Nakashima J, Ohori M, et al. Impact of tumor size on renal function and prediction of renal insufficiency after radical nephrectomy in patients with renal cell carcinoma. J Urol 2011;186(4):1242–6
7. Saika, T., Ono, Y., Hattori, R., Gotoh, M., Kamihira, O.,Yoshikawa, Y., Yoshino, Y., and Ohshima, S. (2003) Long term outcome of laparoscopic radical nephrectomy for pathological T1 renal cell cancer. Urology 62, 1018–1023
8. Wille, A.H., Roigas, J., Deger, S., Tullmann, M., Turk, I., and Loening, S.A. (2004) Laparoscopic Radical Nephrectomy: Techniques, Results and Oncological Outcome in 125 Consecutive Cases. Eur. Urol. 45, 483– 489
9. Saadettin Yilmaz Eskicorapci, Dogu Teber, Michael Schulze, Mutlu Ates, Christian Stock, and Jens J. Rassweiler*(2007), Laparoscopic Radical Nephrectomy: The New Gold Standard Surgical Treatment for Localized Renal Cell Carcinoma, TheScientificWorldJOURNAL (2007) 7, 825–836
10. Lê Xuân Thanh (2019), Results of Laparoscopic Surgery after Radical Nephrectomy for Localized Renal Cell Carcinoma at Viet Duc Friendship Hospital, Master's Thesis, Hanoi Medical University.
11. Nguyễn Việt Dũng (2006) Study of Clinical and Paraclinical Characteristics, Treatment Evaluation, and Prognosis of Adult Renal Cell Carcinoma. Master's Thesis in Medicine.
12. Andrew J. Portis, Yan Yan, Jaime Landman, Cathy Chen, Peter H. Barrett, Donald D. Fentie, Yoshinari Ono, Elspeth M. Mcdougall And Ralph V. Clayman (2002). Long-Term Followup After Laparoscopic Radical Nephrectomy. The Journal Of Urology of AUA, 167, 1257–1262.