ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ PHƯƠNG PHÁP ĐIỀU TRỊ BỆNH NHÂN SARCOMA TỬ CUNG TẠI BỆNH VIỆN PHỤ SẢN TRUNG ƯƠNG

Abstract

Objective: Our study aims to describe some clinical and imaging characteristics and managements of uterine sarcoma. Methods: A retrospective cross-sectional descriptive study was conducted on 35 uterine sarcoma patients diagnosed and treated at the National Hospital of Obstetrics and Gynecology from January 2019 to December 2022. Results: The average age of patients was 51,3 ± 13,7 years-old. 51,4% of patients was menopaused. The most common symtom in uterine leiomyosarcoma was pelvic pain (73,6%), while in endometrial stromal sarcoma and adenosarcoma was post-menopaused vaginal bleeding (75%). In imaging diagnostics, most of them had one tumor with the characteristic of enhanced vascularity (58,8% of uterine leiomyosarcoma and 85% of endometrial stromal sarcoma and adenosarcoma). 15/35 patients were diagnosed correctly as uterine sarcoma before operation, maily due to pre-operated endometrial biopsy. The most common histopathological types were uterine leiomyosarcoma (54,2%) and endometrial stromal sarcoma (42,8%). The predominent initial management was complete hystorectomy (77,3%). Bilateral ovarian resection was applied coincidentally to 68,6 % of them. Of 11/35 patients dissected the pelvic lymph node, 27,3% was positive. Conclusion: Uterine sarcoma was commonly seen in pre-menopause and menopause. Uterine leiomyosarcoma and endometrial stromal sarcoma – adenosarcoma were the most common histopathological type, and they include different clinical and imaging features. The disease was mainly diagnosed after operation. Complete hysterectomy was the predominant mangagement.