SHORT-TERM OUTCOMES OF ANATOMICAL MAJOR HEPATECTOMY FOR HEPATOCELLULAR CARCINOMA

Thế Anh Phạm, Mạnh Cường Trương

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Abstract

Objective: To evaluate the short-term outcomes of anatomical major hepatectomy for hepatocellular carcinoma. Subject and method: This was a retrospective descriptive study of the cases who underwent anatomical major hepatetomy for hepatocellular carcinoma at the Department of Hepatobiliary and Pancreatic Surgery, K Hospital from April 2018 to October 2023. Result: Elective surgery was performed for 207 patients. The average age was 55,5 ± 12,6 years; 87,8% of patients were male; hepatitis B related: 81,3%. The mean AFP was 1575,4 ± 4869,6 ng/ml. Portal vein thrombosis was seen in 24 patients (11,6%).  The mean tumor size in the CT scan was 9,4 ± 4 cm. Right hepatectomy has the majority (53,7%). Takasaki’s method was the majority of extrahepatic Glissonean pedicle isolation (92,1%). The mean operation time was 131,6 ± 35,4 min. There was no intraoperative blood transfusion. The average length of hospital stay was 10,1 ± 6,5 days. Postoperative complications that occurred in 41 patients (20%) including ascites (18,5%), liver failure (2,5%), pleural effusion (1%) and surgical site infection (1%). The classification of complications according to Clavien was: I (17,1%), II (2,4%) and IIIa (0,5%). There was no perioperative mortality. Conclusion: Anatomical major hepatectomy for hepatocellular carcinoma is a feasible, safe, and effective method.

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References

1. IARC G (2020), "Cancer fact sheet: Liver caner incidence and mortality wordwide".
2. Takasaki K (2007), Glissonean pedicle transection method for hepatic resection, Springer Science & Business Media.
3. Menon K V, Al-Mukhtar A, Aldouri A, et al (2006), "Outcomes after major hepatectomy in elderly patients", Journal of the American college of Surgeons, 203 (5), pp. 677-683.
4. Lê Văn Thành (2013), "Nghiên cứu chỉ định và kết quả phẫu thuật cắt gan kết hợp phương pháp Tôn Thất Tùng và Lortat Jacob trong điều trị ung thư biểu mô tế bào gan", Luận án tiến sĩ Y học - Đại học Quân Y.
5. Vũ Văn Quang (2019), "Nghiên cứu ứng dụng kỹ thuật kiểm soát cuống Glisson theo Takasaki trong cắt gan điều trị ung thư biểu mô tế bào gan tại Bệnh viện Trung ương Quân đội 108", Luận án tiến sĩ Y học.
6. Lee C-W, Tsai H-I, Sung C-M, et al (2016), "Risk factors for early mortality after hepatectomy for hepatocellular carcinoma", Medicine, 95 (39).
7. Trịnh Quốc Đạt (2019), "Nghiên cứu ứng dụng kỹ thuật kiểm soát chọn lọc cuống Glisson trong cắt gan điều trị ung thư tế bào gan", Luận án Tiến sĩ Y học - Đại học Y Hà Nội.
8. Belghiti J, Noun R, Malafosse R, et al (1999), "Continuous versus intermittent portal triad clamping for liver resection: a controlled study", Annals of surgery, 229 (3), pp. 369.
9. Nanashima A, Abo T, Hamasaki K, et al (2013), "Predictors of intraoperative blood loss in patients undergoing hepatectomy", Surgery today, 43 (5), pp. 485-493.
10. Yoon Y-I, Kim K-H, Kang S-H, et al (2017), "Pure laparoscopic versus open right hepatectomy for hepatocellular carcinoma in patients with cirrhosis", Annals of surgery, 265 (5), pp. 856-863.