ĐẶC ĐIỂM MẬT ĐỘ XƯƠNG Ở BỆNH NHÂN GÚT CÓ BIẾN CHỨNG BỆNH THẬN MẠN TÍNH ĐIỀU TRỊ TẠI BỆNH VIỆN TRUNG ƯƠNG THÁI NGUYÊN

Abstract

Objective: Describe the characteristics of bone density and some factors related to bone density in gout patients with complications of chronic kidney disease treated at Thai Nguyen Central Hospital. Research subjects and methods: Cross-sectional descriptive study was conducted on 62 gout patients with complications of chronic kidney disease treated at Thai Nguyen Central Hospital. Results: Mean age 70.89 ±10.37. Chronic kidney disease stage: Stage I accounts for 8.1%, Stage II: 45.2%, Stage IIIa: 25.8%, IIIb: 21.0%, estimated MLCT <60 ml/min/ 1.73 m2 skin accounts for 46.8%. The rate of normal bone density is 16.1%, osteopenia is 38.7%, osteoporosis is 45.2%. Average bone density at the lumbar spine -1.99±1.03, average bone density at the femoral neck -1.08±0.91. There is statistical significance between bone density and time to detect gout, appearance of tophi, and treatment compliance (p<0.05). There was no statistical significance between bone density and HGB concentration, total serum calcium, blood uric acid, proteinuria, and erythrocyteuria in the study subjects (p>0.05). Conclusion: The rate of osteoporosis in gout patients with complications of chronic kidney disease is high, the rate of osteoporosis is 45.2%. Average bone density at the lumbar spine -1.99±1.03, at the femoral neck -1.08±0.91, there is a relationship between bone density and time to detect gout, appearing tophi, treatment compliance (p<0.05).