CYTOTOXIC ACTIVITY OF FRACTIONS AND COMPOUNDS FROM PEPEROMIA PELLUCIDA

Tran Khanh Linh 1, Nguyen Thi Anh Lam1, Ngo Thi Quynh-Mai1,
1 Faculty of Pharmacy, Haiphong University of Medicine and Pharmacy, Haiphong, Vietnam

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Tóm tắt

Peperomia pellucida is a widely distributed herb and commonly used in folk medicine for the treatment of various disorders. The present study reported the isolation, elucidation of compounds from the whole plant and their cytotoxic activities on Hep G2 (HB - 8065TM, hepatocellular carcinoma), A549 (CCL-185™, pulmonary adenocarcinoma), and MCF-7 (HTB - 22TM, breast cancer) cell lines. As a result, velutin exhibited the most significant cytotoxicity against Hep G2, A549, and MCF-7 cell lines with IC50 values of 34.00, 30.85, and 41.33 μg/mL, respectively.

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Tài liệu tham khảo

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