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WOUND HEALING RESULTS IN PATIENTS AFTER BRAIN TUMOR SURGERY WHO RECEIVED RADIOTHERAPY
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Abstract
Objective: to evaluate the wound healing results in patients after brain tumor surgery who received radiotherapy. Subjects and methods: patients who underwent brain surgery at K Hospital from November 2022 to October 2023. Patients with a history of radiotherapy or chemo-radiotherapy in the brain (same location as the planned surgery). Good general condition (Karnofsky score above 70 points). Retrospective, cross-sectional study. Results: Total of 30 patients, mean age: 42±15.4, youngest 16 years old, oldest 73 years old. Male 14/30 patients (47.7%), female (53.3%). All patients in this study had undergone irradiation of the surgical area (100%), 23/30 patients (76.7%) had recurrent malignant glioma, and 6/30 patients with brain metastases(20%). Wound healing results: 73.3% had good, 20% had delayed wound healing, no wound healing and skin necrosis (6.7%). The surgical group after 12 weeks of radiation therapy (63.3%) had a good wound healing rate of 18/19 patients, with 1 patient having delayed wound healing. The group of patients who had surgery less than 12 weeks after radiation therapy (36.7%) had good wound healing results of 4 patients (13.3%), slow healing within 3-4 weeks (16.7%), and 2 patients had no wound healing due to skin necrosis in the irradiated area, exposed skull bone (6.7%). Conclusion: The timing of surgery within 12 weeks after radiotherapy for brain tumors affects wound healing results.
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Keywords
brain tumor, radiotherapy, wound healing
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