KHẢO SÁT ĐỘ LỌC CẦU THẬN ƯỚC TÍNH, TỶ SỐ ALBUMIN/CREATININE NIỆU TRÊN BỆNH NHÂN VẢY NẾN

Nhật Trường Nguyễn, Thị Hồng Chuyên Nguyễn, Thế Trung Văn

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Abstract

Objective: To evaluate the estimated glomerular filtration rate (eGFR), urine albumin to creatinine ratio (ACR), and assess their association with clinical characteristics and serum urea levels in patients with psoriasis. Subjects and methods: A cross-sectional study was conducted on 54 patients with psoriasis. Results: The mean eGFR (mL/min/1.73 m²), calculated using the CKD-EPI formula, was 85.02 ± 14.77. The median ACR (mg/g) was 4.76 (2.91–14.18). A significant association was found between eGFR and age, smoking status, psoriasis severity (measured by PASI score), and serum urea levels. Similarly, ACR was significantly associated with age and psoriasis severity (PASI score). Conclusion: Renal function impairment is observed in psoriasis patients, particularly in older individuals, smokers, and those with severe psoriasis. Additionally, serum urea levels tend to rise as glomerular filtration rate decreases.

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References

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