ĐẶC ĐIỂM DI CĂN HẠCH VÀ MỘT SỐ YẾU TỐ LIÊN QUAN CỦA BỆNH NHÂN UNG THƯ DẠ DÀY ĐƯỢC PHẪU THUẬT TRIỆT CĂN TẠI BỆNH VIỆN BẠCH MAI

Abstract

Objective: To assess the lymph node metastasis status and associated factors in gastric cancer patients who underwent radical surgery at Bach Mai Hospital. Methods: A retrospective descriptive study was conducted on 104 gastric cancer patients who underwent radical surgery at Bach Mai Hospital from January 2023 to January 2024. Results: Among the 104 gastric cancer patients studied, 70 were male (67.3%) and 34 were female (32.7%), with the majority being middle-aged and particularly those over 60 years old (75%), with a mean age of 64.9 ± 11.4 years. Histopathologically, 100% of the patients had adenocarcinoma. Partial gastrectomy was the predominant surgical approach (87.5%) compared to total gastrectomy (12.5%). Lymph node metastasis was present in 72 patients (69.2%), with stage N3 having the highest prevalence (29.7%). None of the patients with Tis and T1 stages exhibited lymph node metastasis. However, lymph node metastasis rates for T2, T3, and T4 stages were 64.7% (11/17), 73.1% (19/26), and 81.8% (9/11), respectively, with a statistically significant difference (p=0.001). Among patients with poorly differentiated tumors, the lymph node metastasis rate was 84.9% (45/53), significantly higher than in moderately differentiated tumors (53.1%, 26/49) (p=0.002). Conclusion: The lymph node metastasis rate was 69.2% (72/104 patients), with N1 at 13.5%, N2 at 26.0%, and N3 at 29.7%. Tumor invasion depth, histopathological type, and cellular differentiation grade are factors associated with lymph node metastasis. Increased invasion depth and poorer cellular differentiation are associated with higher lymph node metastasis rates.