GIÁ TRỊ CỦA TROPONIN I TRONG DỰ ĐOÁN NGUY CƠ SUY TIM CẤP SAU PHẪU THUẬT NGOÀI TIM

Abstract

Objective: The objective of this study is to examine the correlation between Troponin I levels and perioperative cardiovascular incidents in medium to high risk patients undergoing non-cardiac surgical procedures at Vinh Phuc Provincial General Hospital. Methods: A cross-sectional descriptive study involving 100 patients scheduled for non-cardiac surgery was performed at Vinh Phuc Provincial General Hospital between October 2023 and September 2024. Troponin I levels were measured preoperatively, on postoperative day 1, and again on postoperative day 3. To evaluate the relationship between biomarker levels and perioperative outcomes occurring within 30 days post-surgery, logistic regression analysis was employed. Results: In a cohort of 100 patients with a mean age of 70 ± 12.6 years, 54% of the participants were female. Troponin I concentrations measured preoperatively, on postoperative day 1, and on postoperative day 3 were recorded as 0.02 ± 0.065 ng/ml, 0.014 ± 0.017 ng/ml, and 0,035 ± 0,129 ng/ml, respectively. Notably, Troponin I levels on day 3 exhibited a significant correlation with the incidence of acute heart failure, yielding an odds ratio of 30,077,121,790.7 (95% CI: 1.17 - 7.72880725607392E+20), with a p-value of 0.049. Conclusion: Troponin I is an important biomarker for assessing acute heart failure in patients undergoing non-cardiac surgery. Elevated levels indicate myocardial stress or injury, aiding in perioperative risk management.