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Date Published: 02/04/2025
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DOI: https://doi.org/10.51298/vmj.v547i3.13153
Issue
Vol. 547 No. 3 (2025)
Section
Các bài báo
How to Cite
Phạm Văn, P., Lê Thi, H., Roãn Thị, H., & Lương Hương, G. (2025). EPIDEMIOLOGICAL, CLINICAL CHARACTERISTICS, AND TREATMENT OUTCOMES IN PATIENTS WITH CANDIDEMIA IN THE INTENSIVE CARE UNIT, NATIONAL HOSPITAL FOR TROPICAL DISEASES. Vietnam Medical Journal, 547(3). https://doi.org/10.51298/vmj.v547i3.13153

EPIDEMIOLOGICAL, CLINICAL CHARACTERISTICS, AND TREATMENT OUTCOMES IN PATIENTS WITH CANDIDEMIA IN THE INTENSIVE CARE UNIT, NATIONAL HOSPITAL FOR TROPICAL DISEASES

Phúc Phạm Văn, Huyền Lê Thi, Hương Roãn Thị, Giang Lương Hương

Main Article Content

Abstract

Objectives: This study aimed to analyze the clinical features of candidemia, treatment outcomes, and factors influencing these outcomes. Subjects and Methods: A retrospective study of 32 patients diagnosed with candidemia in the intensive care unit at the National Hospital for Tropical Diseases from January 2023 to April 2024, collecting clinical and laboratory findings, treatment outcomes, and assessing factors related to treatment outcomes. Result: The incidence of candidemia in the Intensive Care Unit (ICU) was 1.77%. The majority of patients had at least one underlying condition, with cirrhosis being the most prevalent, affecting 71.9% of patients, followed by hypertension (50%) and diabetes mellitus (46.9%). The most isolated Candida species were C. albicans (46.9%), followed by C. tropicalis and C. parapsilosis, which accounted for 28.1% and 18.1%, respectively. The fluconazole resistance rates for C. tropicalis and C. parapsilosis were 40% and 33.3%, respectively. The mortality rate of candidemia patients was 56.3%, associated with factors such as cirrhosis, mechanical ventilation, thrombocytopenia (<150 x109/L), high PT/ INR (>1.5), and elevated bilirubin (>20 mmol/L) at first positive blood culture for Candida.

Article Details

Keywords

Candidemia, intensive care unit (ICU)

References

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