ĐÁNH GIÁ ẢNH HƯỞNG TRÊN MỘT SỐ CHỈ SỐ TUẦN HOÀN, HÔ HẤP KHI GÂY MÊ BẰNG PROPOFOL KIỂM SOÁT NỒNG ĐỘ ĐÍCH DƯỚI HƯỚNG DẪN CỦA CHỈ SỐ LƯỠNG PHỔ BIS

Abstract

Objective: To evaluate the impact on certain circulatory and respiratory indices during anesthesia with target-controlled propofol under bispectral index (BIS) guidance in thyroid cancer surgery. Subjects and Methods: The study included 82 patients diagnosed with thyroid cancer who were undergoing treatment at the Thoracic Surgery Department of 108 Military Central Hospital. These patients were scheduled for near-total or total thyroidectomy between September 2023 and February 2024. Results: Heart rate and mean blood pressure reached their lowest levels just before endotracheal intubation (ETI), then gradually increased and surpassed baseline values (T0). During the induction phase, respiratory rate decreased, while in the recovery phase, it returned to normal. Throughout surgery, all patients maintained an SpO₂ level of at least 93%, with no significant changes in oxygen saturation. The average duration of surgery was 68.38 ± 18.14 minutes, the mean anesthesia emergence time was 12.86 ± 2.88 minutes, and the average time to extubation was 9.17 ± 2.48 minutes. Adverse events during surgery included hypertension (6.10%), bradycardia (4.88%), and tachycardia (2.44%). No cases of respiratory depression or hypotension were recorded. Conclusion: The bispectral index (BIS) is an effective and safe tool for monitoring anesthesia depth and adjusting propofol concentrations during thyroid cancer surgery.