THE CLINICAL, PARACLINICAL AND QUALITY OF LIFE OF PATIENTS WITH ULCERATIVE COLITIS BEFORE AND AFTER INPATIENT TREATMENT
Main Article Content
Abstract
Objective: To assess the quality of life of patients with Ulcerative Colitis (UC) before and after inpatient treatment. Subjects and Methods: A cross-sectional, longitudinal study was conducted on 38 patients aged 18 and over, diagnosed with Ulcerative Colitis, and treated at Bach Mai Hospital and Hanoi Medical University Hospital. Instrument: The IBDQ-32 questionnaire was used to evaluate QoL across four dimensions (bowel symptoms, systemic health, social function, emotional function), with scores ranging from 32-224. QoL improvement was defined as an increase of ≥16 points. Results: Among the 38 UC patients hospitalized for treatment, there were 16 males and 22 females, with an average age of 47.1 ± 15.5 years. The mean IBDQ-32 score increased from 120.63 ± 24.52 (at admission) to 173.34 ± 20.74 (after 8 weeks), a difference of 52.78 ± 14.25 points. This difference was statistically significant (p<0.001). Quality of life scores in each dimension also significantly increased: bowel symptoms (20.05 points), systemic health (9.97 points), social function (8.02 points), and emotional function (14.81 points), with p<0.001 for all. Conclusion: The quality of life of patients with Ulcerative Colitis improved at the 8-week mark compared to before treatment.
Article Details
Keywords
Ulcerative colitis, quality of life, IBDQ-32
References

2. Chen X-L, Zhong L-h, Wen Y, et al. Inflammatory bowel disease-specific health-related quality of life instruments: a systematic review of measurement properties. Health and quality of life outcomes. 2017;15:1-13.

3. Kalantar-Zadeh K, Kopple JD, Block G, Humphreys MH. Association among SF36 quality of life measures and nutrition, hospitalization, and mortality in hemodialysis. Journal of the american society of nephrology. 2001;12(12):2797-2806.

4. Irvine EJ, Feagan B, Rochon J. 5. Quality of Life: A valid and Reliable measure of Therapeutic Efficacy in the Treatment of Inflammatory Bowel Disease. Gastroenterology 1994;106:287 - 296.

5. Eaden J, Abrams K, Mayberry J. The Crohn's and colitis Knowledge score: a test for measuring patient knowledge in inflammatory bowel disease. Am J Gastroenterol. 1999;94(3560-6).

6. Duley-Brown S. Prevention of psychological distress in person with inflammatory bowel disease. Issues Ment Health Nurs 2002;23:403-422.

7. Cohen S, Kamarch T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24(385-96).

8. cohen S, Williamson G. Perceived stress in a probability sample of the United States. The social psychology of health. Newbury Park. 1988.

9. Moradkhani A, Beckman LJ, Tabibian JH. 14. Health-related quality of life in inflammatory bowel disease: Psychosocial, clinical, socioeconomic, and demographic predictors. Journal of Crohn's and Colitis. 2013;7:467-473.

10. Karwowski C, Keljo D, Szigethy E. Strategies to Improve quality of life in adolescent with inflammatory bowel disease. Inflamm Bowel Dis. 2009;15:1755-1764.
