THE CLINICAL, PARACLINICAL AND QUALITY OF LIFE OF PATIENTS WITH ULCERATIVE COLITIS BEFORE AND AFTER INPATIENT TREATMENT

Hiền Nguyễn Thị Thu, Hồng Nguyễn Thị Vân, Nam Nguyễn Hoài, Yến Lỗ Thị, Trang Khúc Thu, Hà Nguyễn Trung, Nhung Trịnh Thị Hồng, Hà Đoàn Thị Ngọc, Thắng Trần Việt, Tài Lê Phú, Hiếu Nguyễn Văn, Long Nguyễn Công

Main Article Content

Abstract

Objective: To assess the quality of life of patients with Ulcerative Colitis (UC) before and after inpatient treatment. Subjects and Methods: A cross-sectional, longitudinal study was conducted on 38 patients aged 18 and over, diagnosed with Ulcerative Colitis, and treated at Bach Mai Hospital and Hanoi Medical University Hospital. Instrument: The IBDQ-32 questionnaire was used to evaluate QoL across four dimensions (bowel symptoms, systemic health, social function, emotional function), with scores ranging from 32-224. QoL improvement was defined as an increase of ≥16 points. Results: Among the 38 UC patients hospitalized for treatment, there were 16 males and 22 females, with an average age of 47.1 ± 15.5 years. The mean IBDQ-32 score increased from 120.63 ± 24.52 (at admission) to 173.34 ± 20.74 (after 8 weeks), a difference of 52.78 ± 14.25 points. This difference was statistically significant (p<0.001). Quality of life scores in each dimension also significantly increased: bowel symptoms (20.05 points), systemic health (9.97 points), social function (8.02 points), and emotional function (14.81 points), with p<0.001 for all. Conclusion: The quality of life of patients with Ulcerative Colitis improved at the 8-week mark compared to before treatment.

Article Details

References

1. Molodecky N, Soon I, Rabi D. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology. 2012;142(46-54).
2. Chen X-L, Zhong L-h, Wen Y, et al. Inflammatory bowel disease-specific health-related quality of life instruments: a systematic review of measurement properties. Health and quality of life outcomes. 2017;15:1-13.
3. Kalantar-Zadeh K, Kopple JD, Block G, Humphreys MH. Association among SF36 quality of life measures and nutrition, hospitalization, and mortality in hemodialysis. Journal of the american society of nephrology. 2001;12(12):2797-2806.
4. Irvine EJ, Feagan B, Rochon J. 5. Quality of Life: A valid and Reliable measure of Therapeutic Efficacy in the Treatment of Inflammatory Bowel Disease. Gastroenterology 1994;106:287 - 296.
5. Eaden J, Abrams K, Mayberry J. The Crohn's and colitis Knowledge score: a test for measuring patient knowledge in inflammatory bowel disease. Am J Gastroenterol. 1999;94(3560-6).
6. Duley-Brown S. Prevention of psychological distress in person with inflammatory bowel disease. Issues Ment Health Nurs 2002;23:403-422.
7. Cohen S, Kamarch T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24(385-96).
8. cohen S, Williamson G. Perceived stress in a probability sample of the United States. The social psychology of health. Newbury Park. 1988.
9. Moradkhani A, Beckman LJ, Tabibian JH. 14. Health-related quality of life in inflammatory bowel disease: Psychosocial, clinical, socioeconomic, and demographic predictors. Journal of Crohn's and Colitis. 2013;7:467-473.
10. Karwowski C, Keljo D, Szigethy E. Strategies to Improve quality of life in adolescent with inflammatory bowel disease. Inflamm Bowel Dis. 2009;15:1755-1764.