DIAGNOSTIC PERFORMANCE OF MAGNETIC RESONANCE IMAGING PERFUSION AND DTI FOR BRAINSTEM GLIOMA GRADING

Anh Đỗ Việt, Hùng Nguyễn Duy, Hệ Đồng Văn

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Abstract

Objective: To study the value of MRI perfusion and diffusion tensor imaging in the diagnosis of brainstem glioma grading. Subjects and methods: The study included 35 patients, including 9 patients with low-grade glioma and 26 patients with high-grade glioma. The characteristics of age, rCBV, rCBF, FA value, MD of solid part of tumor, area around tumor compared with normal parenchyma were compared using Mann-Whitney U test, Shapiro-Wilk test and Chi-square test. The study analyzed ROC curve to determine the cut-off value and diagnostic value of brainstem glioma grading of perfusion MRI and diffusion tensor MRI. Results: Our study showed that the FAt, rFAt, rFAq, rCBVt, rCBFt, rCBVp, rCBVt/l, rCBVp/l indices have diagnostic value in grading brainstem gliomas with AUCs of 0.874, 0.885; 0.838; 0.983; 0.868; 0.859; 0.833 and 0.838, respectively. Conclusion: The FA index on DTI, the rCBV index, rCBF on perfusion MRI between the solid part of the tumor, the around tumor area and the normal parenchyma are valuable in grading brainstem gliomas.

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References

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