RISK FACTORS FOR ACUTE KIDNEY INJURY IN PATIENTS ON INVASIVE VENTILATION IN DEPARTMENT OF CRITICAL CARE MEDICINE

Tú Nguyễn Ngọc, Kiệt Lý Thành, Đại Huỳnh Quang, Duyên Bùi Thị Hạnh, Biên Lê Hữu Thiện, Dương Ngô Thị Thùy, Linh Trần Thanh, Thảo Phạm Thị Ngọc

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Abstract

Background: Invasive ventilation is associated with significant increases in the risk of acute kidney injury. Therefore, it is essential to conduct studies to determine the incidence and identify associated risk factors. Objectives: To determine the incidence of acute kidney injury and the risk factors related to acute kidney injury in patients on invasive ventilation. Methods: A retrospective cohort study with patients on invasive ventilation admitted to Department of Critical Care Medicine at Cho Ray Hospital and the Department of Critical Care Medicine at University of Medical Center of Ho Chi Minh City from December 1, 2023, to August 30, 2024. Results: The incidence of acute kidney injury in patients on invasive ventilation during the first 7 days was 20.88%. Among these patients, stage 2 acute kidney injury as classified by KDIGO, had the highest prevalence at 42.10%. The independent risk factors for acute kidney injury in patients on invasive ventilation included the APACHE II score and plateau pressure. An APACHE II score ≥ 20 and a plateau pressure ≥ 22 cmH2O were significant predictors of acute kidney injury in this population. Conclusions: The incidence of acute kidney injury in patients on invasive ventilation was 20.88%, with the APACHE II score and plateau pressure as independent risk factors.

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References

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