CLINICAL, ULTRASONOGRAPHIC, AND PATHOLOGICAL CHARACTERISTICS OF PATIENTS WITH BREAST LESIONS UNDERGOING ULTRASOUND-GUIDED VACUUM-ASSISTED BIOPSY

Bình Nguyễn Thái, Hương Nguyễn Thị

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Abstract

Objective: To describe the clinical, ultrasonographic, and pathological characteristics of patients undergoing vacuum-assisted biopsy (VABB). Subjects and Methods: A retrospective descriptive study was conducted on 77 patients who underwent VABB at Hanoi Medical University Hospital from January 2020 to April 2025. Results: The mean age in the study was 38.4 years. Clinically palpable lesions were found in 50.6% of cases, and 24.7% of patients reported pain. Among patients undergoing VABB, 51.9% had BI-RADS 3 lesions, while 48.1% had BI-RADS 4 lesions on ultrasound. The mean lesion size was 15.1 mm. BI-RADS 3 lesions were significantly larger than BI-RADS 4 lesions (p<0.05). Malignant pathology was found in 2,6% of cases, with fibroadenoma being the most common histological finding (68.8%). Less common lesions included intraductal papilloma (7.8%), sclerosing adenosis (6.5%), fibrocystic changes (6.5%), and usual ductal hyperplasia (3.9%). The proportion of fibroadenomas was higher in the BI-RADS 3 group than in the BI-RADS 4 group, with a statistically significant difference (p<0.05). Conclusion: Lesions diagnosed and treated with VABB exhibit diverse ultrasound and clinical characteristics. VABB can be used for the removal of benign tumors or for the diagnosis of suspicious malignant lesions (BI-RADS 3-4), with a malignancy rate of 2,6% among the intervened patients.

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References

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