CLINICAL CHARACTERISTICS AND SOME RELATED FACTORS OF MYASTHENIC CRISIS
Main Article Content
Abstract
Background: Myasthenia Gravis is one of autoimmune diseases that effects to neuromuscular junction, typically manifests in muscular weakness. This disease has the different clinical characteristics and progression in each patient, some have early and severe progression with the relapse to myasthenic crisis. In Vietnam, there’ve not been recent studies about risk factors associated with myasthenic crisis. Objectives: To describe the clinical characteristics of myasthenia gravis and identify some factors associated with myasthenic crisis. Materials and methods: The study was conducted on 52 myasthenic patients from February 2023 to December 2024 at Can Tho Central General Hospital. Results: The most common trigger was infection (44,4%), common symptoms were ptosis (94,4%), diplopia (64,8%), limb weakness (51,8%), the fluctuation of muscle weakness in the day and after excersise were common (83,3%), the rate of myasthenic crisis was 13%. Thymoma, history of myasthenic crisis, moderate and severe severity at diagnosis were factors associated with increasing myasthenic crisis, the difference was statistically significant. Conclusion: Myasthenia gravis has diverse and heterogeneous clinical manifestations. Thymoma, history of myasthenic crisis, moderate and severe severity at diagnosis are associated with the occurrence of myasthenic crisis.
Article Details
Keywords
Myasthenia gravis, Myasthenic crisis
References

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