ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG Ở NGƯỜI BỆNH UNG THƯ VÒM MŨI HỌNG

Abstract

Objectives: To investigate the clinical and paraclinical characteristics of nasopharyngeal cancer patients at Hanoi Medical University Hospital and K Hospital. Subjects: A total of 119 patients diagnosed and treated for nasopharyngeal cancer at K Hospital and the Center for Gene and Protein Research - Hanoi Medical University, Hanoi Medical University Hospital. Methods: Cross-sectional study. Results: The most common clinical symptoms of nasopharyngeal cancer were headache (56.3%) and tinnitus (55.5%). Cranial nerve damage was observed in 15.1% of patients. Most lesions identified by endoscopy were exophytic tumors (86.5%), primarily originating from the Rosenmüller fossa (72.3%) and the superior posterior wall (50.4%). Tumor invasion was detected by MRI/CT in 74.8% of patients, with 87.6% of these cases showing extension into the nasal cavity and sinuses. Regarding cervical lymph nodes, 74.8% of patients presented with lymphadenopathy, predominantly involving the high jugular lymph node group (95.5%). Most patients had 1-2 cervical nodes (69.6%), typically unilateral (56.2%). Metastasis was found in 58.4% of cases. TNM classification indicated that most patients were in advanced stages (T3-T4: 44.5%; N1-N3: 74.8%), while 98.3% had no distant metastasis (M0). Conclusion: This study highlights the importance of early recognition of nasopharyngeal cancer characteristics to enhance diagnostic efficacy. The findings provide a scientific basis for improving early detection and treatment strategies for this condition in clinical practice.