MỐI LIÊN QUAN GIỮA NỒNG ĐỘ CANXI HUYẾT THANH VÀ TỬ VONG NỘI VIỆN Ở NGƯỜI BỆNH NHỒI MÁU CƠ TIM CẤP

Abstract

Background: Numerous studies have demonstrated the impact of serum calcium abnormalities on the prognosis of patients with acute myocardial infarction (AMI). This study aimed to evaluate the association between serum calcium level and risk of in-hospital mortality in patients with AMI undergoing percutaneous coronary intervention (PCI). Methods: This was a combined prospective and retrospective descriptive study involving 299 AMI patients treated with PCI at the Interventional Cardiology Department, University Medical Center Ho Chi Minh City, from January 2022 to April 2025. The study population included 20 patients with hypocalcemia (< 2.08 mmol/L) and 279 patients with normal serum calcium level (2.08 – 2.55 mmol/L). Serum calcium was corrected for serum albumin. Results: Serum calcium levels were non-normally distributed, with a median of 2.27 mmol/L and an interquartile range of 2.18–2.33 mmol/L. The hypocalcemia group had a higher proportion of patients classified as Killip class ≥ II and more frequent use of vasopressors, inotropes, and mechanical ventilation. In-hospital mortality was significantly higher in the hypocalcemia group. Logistic regression analysis showed a significant association between hypocalcemia and increased risk of in-hospital mortality, with an odds ratio (OR) of 4.83 (95% CI: 1.58–14.80, p = 0.006). Conclusion: Hypocalcemia is associated with increased in-hospital mortality in patients with acute myocardial infarction undergoing percutaneous coronary intervention.