THE PATIENT HEALTH QUESTIONNAIRE (PHQ – 9): A DEPRESSION SCREENING TOOL FOR PEOPLE WITH EPILEPSY IN VIET NAM

Hoàng Ngọc Trâm Lê

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Abstract

Background: Depression is common among people with epilepsy (PWE) and adversely affects treatment and quality of life, yet remains under‑recognized and undertreated. Objectives: To evaluate the diagnostic accuracy of the Vietnamese Patient Health Questionnaire‑9 (PHQ‑9) as a depression screening tool in PWE. Methods: We conducted a prospective cross‑sectional study at an epilepsy clinic in Ho Chi Minh City (Dec 2019–Mar 2020). Ninety‑one adults with ILAE‑defined epilepsy completed the Vietnamese PHQ‑9 and underwent the Structured Clinical Interview for DSM‑5 (SCID‑5) for major depressive disorder (MDD) as the gold standard. Results: MDD prevalence by SCID‑5 was 25.3%. The PHQ‑9 had an AUC of 0.91. A cut‑point of 8 provided balanced sensitivity 87.0% and specificity 82.4%; at cut‑point 10, specificity was 94.1% and sensitivity 78.0%. Conclusions: The Vietnamese PHQ‑9 is a valid and efficient depression screening tool for PWE in clinic settings

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References

1. Fisher RS, Acevedo C, Arzimanoglou A, et al. ILAE official report: a practical clinical definition of epilepsy. Epilepsia. 2014;55(4):475 482.
2. Fiest KM, Dykeman J, Patten SB, et al. Depression in epilepsy: a systematic review and meta analysis. Neurology. 2013;80(6):590 599.
3. Fiest KM, Patten SB, Wiebe S, Bulloch AG, Maxwell CJ, Jetté N. Validating screening tools for depression in epilepsy. Epilepsia. 2014;55(10):1642 1650.
4. First MB, Williams JBW, Karg RS, Spitzer RL. Structured Clinical Interview for DSM 5 Disorders, Clinician Version (SCID 5 CV). Arlington, VA: American Psychiatric Association; 2016.
5. Kroenke K, Spitzer RL, Williams JB. The PHQ 9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606 613.
6. Nguyen TQ, Bandeen Roche K, Bass JK, et al. The PHQ 9 as a depressive symptom severity measure for sexual minority women in Viet Nam. J Gay & Lesbian Mental Health. 2016;20(2): 173 191.
7. Rathore JS, Jehi LE, Fan Y, et al. Validation of the PHQ 9 for depression screening in adults with epilepsy. Epilepsy & Behavior. 2014;37:215 220.
8. Scheffer IE, Berkovic S, Capovilla G, et al. ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017;58(4):512 521.