KẾT QUẢ ĐIỀU TRỊ VIÊM TỤY CẤP Ở TRẺ EM TẠI BỆNH VIỆN NHI TRUNG ƯƠNG

Abstract

Background: Acute pancreatitis is an acute inflammatory condition of the pancreas characterized by acinar-cell injury due to autodigestion by pancreatic enzymes. Aim: To evaluate treatment outcomes of acute pancreatitis in children at Vietnam National Children’s Hospital. Materials and ethods: A descriptive study of 70 patients diagnosed with acute pancreatitis according to the INSPPIRE criteria and the 2012 revised Atlanta classification from July 2024 to June 2025. Result: The median age was 4.8 years and female predominated. Mild acute pancreatitis accounted for 87,3% of cases. In the moderately severe- severe group, both the duration of fasting and and duration of exclusive hydrolyzed formula feeding were significantly longer, and the use of antibiotics, Octreotide and anticoagulants was more frequently compared with the mild group. Children with moderately severe - severe disease had a higher proportion of hospital stays longer than 14 days (p=0.045), and experienced longer durations of abdominal pain and fever (p=0,002 and p=0.015, respectively). White blood cell count, neutrophil percentage, C-reactive protein, lipase and D-Dimer levels were significantly higher in the moderate – severe and severe group. All markers trended downward over time, although CRP and D-Dimer increased within the first 48 hours before falling markedly by discharge.Conclusions: Most cases of acute pancreatitis in children are mild and can be successfully managed with pancreatic rest and adequate fluid therapy, whereas moderate to severe acute pancreatitis requires the use of antibiotics, proton pump inhibitor therapy, andanticoagulation, and is associated with longer hospital stays.