KIỂM SOÁT ĐƯỜNG HUYẾT Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÍP 2 CÓ BỆNH THẬN MẠN GIAI ĐOẠN 3

Abstract

Objectives: To describe clinical and laboratory characteristics of hospitalized type 2 diabetes mellitus (T2DM) patients with stage 3 chronic kidney disease (CKD3), and to evaluate inpatient glycemic control (GC) outcomes and related factors. Methods: A cross-sectional descriptive study with analysis was conducted on 82 T2DM patients with CKD3 hospitalized at Bach Mai Hospital. Clinical, laboratory, and blood glucose data were collected. Good GC was defined as ≥60% of capillary blood glucose readings within the 5.6-10mmol/L target over 5 days. Appropriate statistical tests and multivariate logistic regression were used. Results: Mean age was 72.2 ± 11.4 years; mean T2DM duration was 13.4 ± 8.7 years. The main reason for admission was high blood sugar (36.6%). Mean baseline HbA1c was 9.4 ± 2.3%; mean eGFR was 43.9 ± 8.8 ml/min. Good inpatient GC was achieved in 42.7%; the hypoglycemia rate was 23.2%. Independent factors associated with good GC included: reason for admission ("Infection" OR=8.4; "Other" OR=9.0 vs. "High blood sugar"), admission blood glucose (OR=1.14), and average insulin dose (OR=0.061). Conclusion: T2DM patients with CKD3 often present with poor baseline GC. Good inpatient GC was achieved in 42.7%, but with a significant hypoglycemia rate. Reason for admission, admission blood glucose, and insulin dose are important predictors for inpatient GC.