NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG CÁC TRƯỜNG HỢP TỔN THƯƠNG VÚ KHÔNG SỜ THẤY TRÊN LÂM SÀNG ĐƯỢC SINH THIẾT TRỌN TẠI BỆNH VIỆN TỪ DŨ

Abstract

Objective: Determine the malignancy rate and the association between certain clinical characteristics, ultrasound imaging features, and the risk of malignancy in biopsied lesions. Subjects and Methods: A cross-sectional study was conducted from July 2023 to August 2024, involving 201 cases that met the inclusion criteria out of 211 lesions biopsied at the Gynecologic Oncology Department and the Gynecology Outpatient Department of Tu Du Hospital. Results: The malignancy rate was 7.6%. Factors associated with an increased risk of malignancy included: women aged 45 years or older (OR = 3.49, 95% CI: 1.07–11.36, P = 0.038). On ultrasound, irregular shape (OR = 2.34, 95% CI: 1.29–4.22, P = 0.005), spiculated margins (OR = 154, 95% CI: 6.89–3442.5, P = 0.001), angular margins (OR = 18.12, 95% CI: 1.9–172.48, P = 0.012), posterior acoustic shadowing (OR = 4.8, 95% CI: 1.12–20.57, P = 0.035), ductal dilatation (OR = 3.51, 95% CI: 1.13–11.25, P = 0.029), and increased vascularity (OR = 3.49, 95% CI: 1.01–12.01, P = 0.047) were all significantly associated with malignancy. Conclusion: Intraoperative imaging verification of the excised specimen using ultrasound or mammography is recommended to minimize the risk of sampling the wrong lesion.