TÁC NHÂN VI SINH GÂY VIÊM PHỔI MẮC PHẢI CỘNG ĐỒNG Ở NGƯỜI LỚN NHẬP VIỆN CÓ HAY KHÔNG CÓ ĐÁI THÁO ĐƯỜNG

Abstract

Background: Community-acquired pneumonia in diabetic patients often progresses seriously and has a high mortality rate. Therefore, accurately identifying the microbiological agents causing community-acquired pneumonia in diabetic patients contributes to improving treatment effectiveness, minimizing complications and effective prevention. Aims: Determine the rate of microbiological agents causing community-acquired pneumonia in hospitalized adults with and without diabetes mellitus and its relationship. Methods: This study was a cross-sectional descriptive design in prospect conducted on sputum of hospitalized community-acquired pneumonia patients with and without diabetes mellitus. The research method used multiplex real-time PCR technique to identify pathogens and chi-square test to determine the relationship. Results: The highest proportion of bacteria causing community-acquired pneumonia in patients with and without diabetes included K. pneumoniae, A. baumannii, H. influenzae, E. coli, and S. pneumoniae. Influenza virus and Candida accounted for the majority in both groups of patients, but Influenza virus type B and Candida albicans as well as Candida tropicalis were detected at a higher rate in diabetic patients than in patients without diabetes with p < 0.05. Conclusions: Gram-negative bacteria, Influenza virus, and Candida fungi accounted for the majority in the two groups of patients, but Influenza virus type B, Candida albicans, and Candida tropicalis are detected in patients with diabetic mellitus at a higher rate than in patients without diabetes mellitus and the difference is statistically significant (p < 0.05).