ỨNG DỤNG THANG ĐIỂM REFIT MELD TRONG TIÊN LƯỢNG TỬ VONG BỆNH NHÂN XƠ GAN MẤT BÙ

Abstract

Early prognostication in patients with cirrhosis is essential. Several prognostic scoring systems have been developed, among which the Refit MELD score—an updated version of the traditional MELD score—has demonstrated significant utility in predicting 90-day mortality in patients with cirrhosis. OBJECTIVE: A retrospective descriptive study was conducted on 120 patients with decompensated cirrhosis admitted to Hanoi Medical University Hospital and Bach Mai Hospital between July 2023 and June 2024. RESULTS: The mean age of patients was 55.58 ± 9.9 years, with males accounting for 90% of the study population. The most common etiology was alcohol-related liver disease (70.8%), followed by hepatitis B virus infection (24.2%) and hepatitis C virus infection (5%). The mean Refit MELD score was 16.17 ± 6.26. The Refit MELD score demonstrated prognostic value for 30-day mortality, with an AUROC of 0.871 (p < 0.05), and for 90-day mortality, with an AUROC of 0.798 (p < 0.05). The AUROC values for the Refit MELD and MELD scores in predicting 90-day mortality were 0.798 and 0.794, respectively. The optimal cutoff values were 15 for Refit MELD and 14 for MELD, both showing statistically significant predictive value for mortality (p < 0.05). Conclusion: The Refit MELD score is a valuable tool for predicting 90-day mortality in patients with decompensated cirrhosis.