INVESTIGATION OF HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES OF PATIENTS WITH NON-HODGKIN LYMPHOMA

Van Phong Hoang 1,, Manh Quan Ngo 2, Ngoc Dung Nguyen 2, Thi Thu Huyen Nguyen 3
1 Center for Hematology - Blood Transfusion, Vietnam- Czech friendship hospital
2 National Institute of Hematology - Blood Transfusion
3 Internal medical department, Vietnam- Czech friendship hospital

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Tóm tắt

       Non-Hodgkin’s lymphoma is one of the ten most common cancers in Vietnam and in many other countries, ranking fifth in morbidity and sixth in mortality after lung, liver, stomach, colorectal cancer. In the United States, in 2008 there were about 66,000 new cases. According to the statistics of the Vietnam National Cancer hospital for the 10 years from 1979 to 1988, there were 1568 new cases, accounting for 7.6%, ranking fifth in total cancer. Objectives: To characterize histopathological and immunohistochemical characteristics of non-Hodgkin lymphoma at the Hai Phong Vietnam- Czech friendship Hospital. Study subjects: Patients diagnosed with non-Hodgkin’s lymphoma in the lymph nodes at the Hai Phong Vietnam - Czech friendship Hospital, from 1/2015 to 9/2018. Study method: Descriptive method described through cross-sectional survey. Results of the study: The most common nodal lesions were nodal metastasis (80.9%), WF7 (54,0%), the WHO classification in 2008, in B-cell lymphoma, the Diffuse large B-cell lymphoma occurred in 80,2% of the patients. In T-cell subtype, peripheral T-cell lymphoma accounted for the highest rate of 40,0%, major cell differentiation (33.4%).

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