INVESTIGATION OF HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES OF PATIENTS WITH NON-HODGKIN LYMPHOMA
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Abstract
Non-Hodgkin’s lymphoma is one of the ten most common cancers in Vietnam and in many other countries, ranking fifth in morbidity and sixth in mortality after lung, liver, stomach, colorectal cancer. In the United States, in 2008 there were about 66,000 new cases. According to the statistics of the Vietnam National Cancer hospital for the 10 years from 1979 to 1988, there were 1568 new cases, accounting for 7.6%, ranking fifth in total cancer. Objectives: To characterize histopathological and immunohistochemical characteristics of non-Hodgkin lymphoma at the Hai Phong Vietnam- Czech friendship Hospital. Study subjects: Patients diagnosed with non-Hodgkin’s lymphoma in the lymph nodes at the Hai Phong Vietnam - Czech friendship Hospital, from 1/2015 to 9/2018. Study method: Descriptive method described through cross-sectional survey. Results of the study: The most common nodal lesions were nodal metastasis (80.9%), WF7 (54,0%), the WHO classification in 2008, in B-cell lymphoma, the Diffuse large B-cell lymphoma occurred in 80,2% of the patients. In T-cell subtype, peripheral T-cell lymphoma accounted for the highest rate of 40,0%, major cell differentiation (33.4%).
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Keywords
Non-Hodgkin’s lymphoma, B cell lymphoma, T cell lymphoma
References
2. Toan, V. Q. 2006. Clinical, paraclinical and treatment result of malignant neck non-Hodgkin lymphoma at K hospital 2000 - 2005. Master thesis in medicine. Hanoi Medical University. (In Vietnamese)
3. Khanh, B. Q., Lan, M., Thanh, N. H., Huong, T. T. M., Binh, V. T., Tri, N. A. 2008. Result of diagnosis and treatment of malignant non-Hodgkin lymphoma. Journal of Medical Practice. 2-3: 11-28
4. Mai, N. T. 2011. Some clinical, paraclinical and some prognostic factors of malignant non-Hodgkin lymphoma at K hospital, 2007 - 2011.
5. Roanh, L. D., Hung, N. P. 2003. Malignant non-Hodgkin lymphoma; Immune phenotype and application of WHO 2001 classification. Medical Journal, 489:291295.
6. Tung, T. T., Lien. P. B., Duy, T. B. 2008. Diagnosis and treatment of non-Hodgkin lymphoma at Cho Ray Hospital from 1/2006 - 12/2007. Vietnam Medial Journal, 2: 107-111.
7. Shalmon, S. The 10th Asia Pacific IAP Congress (Bali - Indonesia 2017), Follicular Lymphoma in the department of anatomical pathology faculty of medica universitas Indonesia 2012-2014: Histology and Immunoprofile.
8. Aukema, S. M. 2011. Double hit B-cell Lymphomas. Blood, 117(8).
9. Savage, K. J., Chhanabhai, M., Gascoyne, R. D., Connor, J. M. 2004. Characterization of peripheral Tcell lymphomas in a single North American institution by the WHO classification.
10. Zukerberg, L. R., Medeiros, L. J., Ferry, J.K., Harris, N.L. 1993. Diffuse low-grade B-cell lymphomas, Four clinically distinct subtype defined by a combination of morphologic and immunophenotypic features, 100(4): 373-85
11. Picker, L. J., Weiss, L. M., Medeiros, L. J., Wood, G. S., Warke, R. A . 1987. Immunophenotypic Criteria for the diagnostic of non-Hodgkin lymphoma. America Journal of Pathology, 128(1): 180-202.