COMMENT ON THE LYMPHO NODE METASTASIS DIAGNOSIS IN NON-SMALL CELL LUNG CANCER PATIENTS WHO HAD TREATED BY VIDEO-ASISTED-THORACOSCOPIC SURGERY AT MILITARY HOSPITAL 103

Vũ Anh Hải, Lê Việt Anh, Nguyễn Văn Nam

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Abstract

Objectives: Evaluate the results of lymph node harvest for N stage determination on non-small cell lung cancer (NCLC) patients by video-assisted-thoracoscopic surgery (VATS). Calculate the sensitivity, specificity of computed tomography (CT) and PET/CT for lymph node metastasis diagnosis. Subjects and methods: A descriptive study on 80 non-small cell lung cancer patients who had been lobectomy and lymph node harvest by VATS. Results: The male/female ratio was 4.7/1, the average of age was 55.9 ± 8.9. The type of histology consists mainly of adenocarcinoma (95%), squamous cell was 5%. The preoperative TNM stage consist of IA (40%), IB (15%), IIA (17.5%), IIB (17.5%) and IIIA (10%). Distribution of lobectomy was mainly the upper lobe (31.2% on the right and 23.8% on the left). The average station number of N1 and N2 lymph nodes removed was 1.8±0.8 and 1.8±0.7, respectively. The sensitivity (Se) and specificity (Sp) of CT in the diagnosis of N1 lymph node metastasis were 50.0% and 83.8%, N2 were 62,5% and 86,1%. The results was better by PET/CT: Se=97.7%, Sp=83.3% for N1 and Se=97,5%, Sp=83,3% for N2. Conclusion: Lympho node harvest by VATS was feasible and effective. Application of CT and PET/CT in diagnosis of lymph node metastasis had good results.

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