REVIEW SOME CLINICAL FEATURES OF HYPERPARATHYROIDISM

Ánh Ngọc Nguyễn1,, Ngọc Lương Trần1, Văn Viện Mai2
1 Endocrine central hospital
2 108 Military Central Hospital

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Abstract

Objectives: To review some clinical features of hyperparathyroidism. Subjects and methods: A prospective, cross-sectional study of 244 patients with hyperparathyroidism (HPT) diagnosed and treated by surgery at the National Hospital of Endocrinology from 03/2016 to 10/2019. Results: A total of 244 patients included 38 cases primary HPT (pHPT), 141 cases secondary HPT (sHPT), 65 cases tertiary HPT (tHPT). The mean age was 43.5±11.8 years old. The most common age group is 31- 60 year-old. The proportion of women of pHPT is significantly higher than that of men, but the percentage of men of sHPT and tHPT is higher than that of women. Symptoms of bone pain and fatigue 100% in secondary and tertiary HPT, pHPT: bone pain 55.3%, fatigue 76.3%. Urinary and urinary disorders were found in 100% of sHPT and tHPT, only 42.1% of pHPT. Clinical examination revealed a pathological mass in the parathyroid gland region 52.2%, mainly lower parathyroid gland (79.2%). Conclusion: Hyperparathyroidism manifests clinically mainly on bones, kidneys, nerves and a pathological mass is found. The clinical symtomps in both the sHPT and tHPT are more obvious and diversified than the pHPT.

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References

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