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Date Published: 25/09/2023
Abstract Views: 194
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DOI: https://doi.org/10.51298/vmj.v530i1B.6672
Issue
Vol. 530 No. 1B (2023)
Section
Các bài báo
How to Cite
Nguyễn, T. T. H., Nguyễn, H. T., Tạ, M. H., & Vũ, V. T. (2023). EFFECTS OF LOW DOSE KETAMINE COMBINED PROPOFOL-TCI ON HEMODYNAMIC DURING INDUCTION FOR ELDERLY PATIENTS. Vietnam Medical Journal, 530(1B). https://doi.org/10.51298/vmj.v530i1B.6672

EFFECTS OF LOW DOSE KETAMINE COMBINED PROPOFOL-TCI ON HEMODYNAMIC DURING INDUCTION FOR ELDERLY PATIENTS

Thị Thu Hà Nguyễn1,, Hữu Tú Nguyễn1, Minh Hiền Tạ1, Văn Trịnh Vũ2
1 HMU
2 GERMANY FRIENDSHIP HOSPITAL

Main Article Content

Abstract

Introduction: Hemodynamic instability has been a problem to concern in elderly patients, especially during induction. Various methods have been recommended to prevent that including TCI propofol. This studies effects of Propofol-TCI combined with low dose ketamine in induction for elderly under general anesthesia. Patients and methods: Sixty patients aged 60 or more years old with ASA I or II were divided randomly into two groups to receive either Propofol-TCI (group I) or Propofol-TCI combined with ketamine (0,5mg/kg; administered 2 minutes before propofol; group II). Heart rate, blood pressure, bispectral index (BIS) and TOF were recorded every 1minute. Fentanyl (2µg/kg); atracurium (0,8mg/kg) were given after target concentration defined. Intubation was performed after TOF=0. Results: The number of patients having severe hypotension was significantly lower in group II (low dose ketamine combined Propofol –TCI) and total dose of ephedrine as well, with p < 0,05. The heart rate was more stable than the one in control group.

Article Details

Keywords

Elderly anesthesia; ketamine, TCI-propofol, induction induced hypotension

References

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