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VALUE OF MULTI-PARAMETRIC MRI, TOTAL PSA INDEX AND FREE/TOTAL PSA RATIO IN DIAGNOSIS OF PROSTATE CANCER AT HUU NGHI HOSPITAL IN 2023
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Abstract
Objectives: Evaluate the effectiveness of detecting prostate cancer lesions using multiparametric magnetic resonance imaging (mp-MRI) technique and PSA indices. Subjects and methods: Retrospective study on 56 patients with suspected prostate cancer mp- MRI, prostate biopsy at Huu Nghi hospital from January 2022 to January 2023 satisfied the patient selection and exclusion criteria, with total PSA index, free/total PSA ratio, combine methods and compare with pathology results on transrectal prostate biopsy. Results: Average age is 72,58 ± 6.89, average prostate volume is 55,47±31,81ml, average total PSA concentration is 35.84±28 ng/ml, free/total ratio PSA mean was 0.16±0.06. The number of prostate cancer patients is 47, accounting for 83,9%. The PIRADS classification with the highest incidence is PIRADS 4 and 5. Applying the free/total PSA index (cut off point is 0,15) and combining the total PSA index with mp MRI has high value in diagnosing prostate cancer with AUC of 0,85 and 0,82. Conclusion: Using mp-MRI combined with total PSA has high diagnostic value in prostate cancer, the free/total ratio with a threshold value of 0.15 has a high value to suggest prostate cancer.
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Keywords
mp MRI, PSA index, prostate cancer
References
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