ĐẶC ĐIỂM KHÁNG KHÁNG SINH CỦA MỘT SỐ VI KHUẨN GÂY BỆNH PHÂN LẬP TỪ BỆNH PHẨM NƯỚC TIỂU TẠI BỆNH VIỆN QUÂN Y 103

Abstract

Objective: Studying the antimicrobial characteristics of bacterial pathogens isolated from urine specimens at Military Hospital 103 from September 2022 to March 2023. Subject and methods: This was a descriptive study. The study subject was bacteria strains isolated from urine of patients at Military Hospital 103 from September 2022 to March 2023. The study variables included bacterial culture results, identification, and antimicrobial susceptibility testing. Results: Escherichia coli was most resistant to ampicillin (86.67%) and trimethoprim/sulfamethoxazole (66.67%) and most sensitive to ertapenem (100%), nitrofurantoin (97.78%), and amikacin (95.56%). Klebsiella spp. was totally resistant to ampicillin, ceftazidime, and cefotaxime and least resistant to amikacin (25.00%). Pseudomonas aeruginosa was highly resistant to most tested antibiotics, ranging from 85.71% to 89.66%. Enterococcus spp. was totally resistant to amikacin, oxacillin, and tobramycin. By contrast, Enterococcus spp. was totally sensitive to linezolid, tigecyline, and teicoplanin and still highly sensitive to vancomycin (96.55%). The rate of multidrug-resistant strains of Klebsiella spp. (95.83%), P. aeruginosa (86.21%), and E. coli (77.78%) was very high. Conclusion: Our study indicates that the proportion of resistance of common bacteria causing urinary tract infection was high, especially K. pneumoniae spp. and P. aeruginosa. The rate of multidrug-resistant strains of Klebsiella spp., P. aeruginosa, and E. coli was extremely high. This study’s result suggested the need for the implementation of infection control measures to limit the spread of antimicrobial-resistant bacteria, especially multidrug-resistant bacteria.