EVALUATION OF THE PROGNOSTIC VALUE OF THE MAP (ASH) SCORE IN EARLY REBLEEDING AND IN-HOSPITAL MORTALITY IN CIRRHOTIC PATIENTS WITH GASTROINTESTINAL BLEEDING FROM ESOPHAGEAL VARICES AND GASTRIC VARICES

Thị Huyền Trang Nguyễn1, Thị Ánh Tuyết Trần 1, Văn Mạnh Nguyễn 1, Tùng Lâm Trần 1, Anh Tuấn Nguyễn 1, Trường Giang Đinh 1, Thị Huế Nguyễn1, Thị Hoài Mai 1, Thanh Bình Mai1,
1 108 Military Central Hospital

Main Article Content

Abstract

Objective: Assess the value of the MAP (ASH) score in predicting early rebleeding and in-hospital mortality in patients with cirrhosis experiencing gastrointestinal bleeding (GIB) due to ruptured esophageal varices (REV) and gastric varices (GV). Subjects and Methods: A cross-sectional descriptive study, non-control group, combined retrospective and prospective study on 197 cirrhotic patients with complications of GIB from REV and GV treated at Military Central Hospital 108 from September 2022 to December 2023. MAP (ASH) scores were calculated and compared with early rebleeding and in-hospital mortality rates. The predictive value was also compared with the Child-Pugh and AIMS65 scores. Results: The average MAP (ASH) score was 3.64 ± 1.68. The MAP (ASH) score showed good predictive value for in-hospital mortality with an AUROC of 0.812; 95% CI: 0.704-0.920; P < 0.01. At a cut-off of 5, it had a sensitivity of 55.6% and a specificity of 92.2%. The MAP (ASH) score demonstrated acceptable predictive value for early rebleeding with an AUROC of 0.787; 95% CI: 0.659-0.916, P < 0.01. At a cutoff of 4, it had a sensitivity of 71.4% and a specificity of 78.1%. Regarding early rebleeding, the MAP (ASH) score performed better predictive value than the Child-Pugh score, while regarding in-hospital mortality,  there was no significant difference among the three scoring systems. Conclusion: The MAP (ASH) score is a valuable prognostic tool for predicting the risk of early rebleeding and in-hospital mortality in cirrhotic patients with GIB complications from REV and GV.

Article Details

References

1. Lâm Tú Hương, et al., Giá trị thang điểm MAP(ASH) trong tiên lượng xuất huyết tiêu hóa trên không do tăng áp lực tĩnh mạch cửa. Y học Cộng đồng, 2023. 76: p. 412-417.
2. Võ Duy Thông, Đặc điểm lâm sàng và cận lâm sàng của xuất huyết tiêu hóa do vỡ dãn tĩnh mạch thực quản ở bệnh nhân xơ gan báng bụng. Tạp chí y học TP Hồ Chí Minh, 2016. 20: p. 307–312.
3. de Franchis, R., et al., Baveno VII - Renewing consensus in portal hypertension. J Hepatol, 2022. 76(4): p. 959-974.
4. Garcia-Tsao, G., et al., Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of liver diseases. Hepatology, 2017. 65(1): p. 310-335.
5. Li, Y., et al., Comparisons of six endoscopy independent scoring systems for the prediction of clinical outcomes for elderly and younger patients with upper gastrointestinal bleeding. BMC Gastroenterol, 2022. 22(1): p. 187.
6. Liver., E.A.f.t.S.o.t., EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis. J Hepatol, 2018. 69(2): p. 406-460.
7. Redondo-Cerezo, E., et al., MAP(ASH): A new scoring system for the prediction of intervention and mortality in upper gastrointestinal bleeding. J Gastroenterol Hepatol, 2020. 35(1): p. 82-89.
8. Zou, D., et al., Albumin-bilirubin score for predicting the in-hospital mortality of acute upper gastrointestinal bleeding in liver cirrhosis: A retrospective study. Turk J Gastroenterol, 2016. 27(2): p. 180-6.