ẢNH HƯỞNG CỦA CÁC ĐẶC ĐIỂM SINH SẢN, LỐI SỐNG ĐẾN NỒNG ĐỘ AMH Ở PHỤ NỮ TIỀN MÃN KINH

Abstract

Anti-mullerian Hormone (AMH) is a reliable marker of ovarian reserve and reproductive aging in premenopausal women. Objectives: Relationship between reproductive factors and lifestyle with AMH levels in premenopausal women. Subjects and methods: Cross-sectional study, performed on 140 women in premenopausal age. Information collection, clinical characteristics by interview questionnaire. AMH and sex hormone assays were performed on a Cobas E801 machine by electroluminescence immunoassay. Results: There was a difference in menstrual status, menstrual cycle characteristics and FSH, LH, E2 tests in 2 groups of normal AMH and low AMH with p<0,05. Low levels of AMH were associated with increasing age with odds ratio OR = 0,83 with 95%CI 0,69 – 0,98. There is a correlation between short menstrual cycle, long cycle/amenorrhea <12 months with low AMH concentration with OR (95%CI) of 6,15 (1,29 – 29,19); 7,1 (1,69 – 29,81). FSH, LH, and E2 levels were significantly lower in the group with lower AMH levels than in the normal AMH group. FSH, LH and E2 levels were significantly lower in the group with lower AMH levels than in the normal AMH group. Conclusions: Low AMH levels are associated with menstrual status, menstrual cycle characteristics and with some endocrine hormones in the perimenopausal.