MỘT SỐ ĐẶC ĐIỂM DI CĂN HẠCH Ở BỆNH NHÂN CẮT GAN DO UNG THƯ ĐƯỜNG MẬT TRONG GAN TẠI BỆNH VIỆN K

Abstract

Objective: To describe some characteristics of lymph node metastasis in patients undergoing liver resection for intrahepatic cholangiocarcinoma (ICC) at K Hospital. Methods: A retrospective descriptive study was conducted on 33 patients who underwent liver resection with hepatoduodenal ligament lymph node dissection for ICC at the Department of Hepatobiliary and Pancreatic Surgery, K Hospital, from October 2021 to December 2023. Results: The male-to-female ratio was 0.8:1; the mean age was 58.8 ± 11.1 years. Types of liver resection included 14 right hepatectomies and 19 left hepatectomies. CA 19-9 and CEA were elevated in 57.6% and 9.1% of cases, respectively. The majority of patients had only one tumor on abdominal CT (93.9%), with a mean tumor size of 5.18 ± 1.98 cm. Lymph node metastasis was present in 45.5% of patients. Patients in stage IIIB had the highest proportion (45.5%). Age > 60 years, gender, tumor size > 5 cm, type of liver resection, CA 19-9 level, satellite nodes, and tumor differentiation were not associated with lymph node metastasis (p > 0.05). There was an association between vascular invasion and lymph node metastasis (p = 0.026). Conclusion: Vascular invasion is associated with lymph node metastasis in patients undergoing liver resection for intrahepatic cholangiocarcinoma with regional lymph node dissection. Further studies with a larger sample size are needed to confirm these findings.