COLD ATMOSPHERIC PLASMA ON TREATMENT CUTE SKIN LESSIONS IN DIABETES PATIENT: A CASE REPORT

Đỗ Thị Quỳnh1, Lương Thanh Tú2, Vũ Thị Thơm1, Đỗ Hoàng Tùng3, Lê Ngọc Thành2, Nguyễn Đình Minh2
1 University of Medicine and Pharmacy, Vietnam National University, Hanoi
2 E Hospital
3 Vietnam Academy of Science and Technology

Main Article Content

Abstract

Many studies show that cold plasma treatment gives many positive results in wound healing. In a case of a patient with Diabetes who had a large wound on the face and arm, we treated the patient's plasma with a PlasmaMed device with a time of 30 seconds/cm2 of wound area per day. The patient was treated for ulcers according to standard procedures, ulcer size, infection status and sensation in the wound area were recorded weekly. After 5 weeks, the lessions was completely epithelialized, no inflammation and abnormal sensation were noted at the CAP treated wound areas.

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References

1. Nguyen Bich Ngoc, Zhou Lu Lin và Waqas Ahmed (2020), "Diabetes: What challenges lie ahead for Vietnam?", Annals of global health. 86(1).
2. Harold Brem 1, Marjana Tomic-Canic (2007), “Cellular and molecular basis of wound healing in diabetes”, J Clin Invest ;117(5).
3. Daniela Boehm và Paula Bourke (2019), “Safety implications of plasma-induced effects in living cells – a review of in vitro and in vivo findings”, Biol. Chem ; 400(1): 3–17.
4. Christian Wetzler và các cộng sự (2000), "Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair", Journal of Investigative Dermatology. 115(2): 245-253.
5. Anita B Roberts (1995), "Transforming growth factor‐β: activity and efficacy in animal models of wound healing", Wound Repair Regeneration. 3(4): 408-418.
6. S Fathollah và cộng sự (2016), "Investigation on the effects of the atmospheric pressure plasma on wound healing in diabetic rats", Scientific reports. 6(1):1-9.
7. Shahriar Mirpour và cộng sự (2020), "Cold atmospheric plasma as an effective method to treat diabetic foot ulcers: A randomized clinical trial", Scientific Reports. 10(1): 1-9.
8. Apirag Chuangsuwanich và cộng sự (2016), "The healing effect of low-temperature atmospheric-pressure plasma in pressure ulcer: a randomized controlled trial", The international journal of lower extremity wounds.15(4): 313-319.