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ANTIMICROBIAL SUSCEPTIBILITY PATTERNS OF AEROMONAS SPP. ISOLATED AT BAC NINH GENERAL HOSPITAL FROM 2019 TO 2023
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Abstract
Aeromonas spp. are pathogenic bacteria associated with a diverse range of infections in humans, presenting a notable 60% mortality rate. Notably, these bacteria exhibit resistance to β-lactam antibiotics. Methods: This cross-sectional study aims to to ascertain epidemiological characteristics and antibiotic resistance patterns of Aeromonas spp. strains isolated at Bac Ninh General Hospital from 2019 to 2023. Results: Out of 42 isolated Aeromonas spp. strains, 35.7% were derived from patients aged ≥ 60 years, 78.6% from male individuals, 54.8% from surgical departments, and 73.8% from wound fluid samples. A. hydrophila predominated among the isolated strains (76.2%), followed by A. veronii (19.0%) and A. salmonicida (4.8%). The resistance profile of Aeromonas spp. strains revealed the highest resistance to Trimethoprime-Sulfamethoxazole (34.5%) and the lowest to Amikacin (7.1%). Notably, Imipenem exhibited the lowest susceptibility rate (36.8%). Conclusions: Amikacin emerges as the optimal antibiotic for treating Aeromonas spp.-induced infections. Vigilant surveillance of antibiotic resistance and robust infection control measures are imperative due to the resistance of Aeromonas spp. to multiple antibiotics.
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References
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