SO SÁNH ĐẶC ĐIỂM DỊCH TỄ VIÊM NÃO TỰ MIỄN DO KHÁNG THỂ KHÁNG THỤ THỂ N-METHYL-D-ASPARTATE VÀ CÁC VIÊM NÃO KHÁC TẠI TRUNG TÂM THẦN KINH BỆNH VIỆN BẠCH MAI NĂM 2023

Abstract

Objective: Comparison of Epidemiological Characteristics between Anti-N-Methyl-D-Aspartate Receptor Encephalitis and Other Types of Encephalitis at Bach Mai Hospital Neurology Center in 2023. Subjects: We selected 126 who were diagnosed with encephalitis at Bach Mai Hospital from January 1^st 2023 to October 31^st, 2023. Methods: Cross-sectional descriptive study. Results: Among 126 encephalitis patients studied, autoimmune encephalitis accounted for the highest rate (49.2%), and infectious encephalitis accounted for the lowest rate (3.2%). Autoimmune encephalitis due to anti-NMDA receptor antibodies accounted for the majority of autoimmune encephalitis with a rate of 74.2%. The incidence of autoimmune encephalitis due to anti-NMDA receptor antibodies was highest in February, September, and October; the incidence of viral encephalitis was highest in June and lowest in March and August; infectious encephalitis had the highest incidence in October. In terms of men, encephalitis of unknown cause accounted for the largest proportion. Among women, NMDA encephalitis accounted for the largest proportion. The average age of NMDA encephalitis is the lowest (30.22). The average age of viral brain pellets was highest (51.32). There were differences in the type of encephalitis between men and women. In the group of patients with encephalitis, women were 3.83 times more likely to develop NMDA encephalitis than men, with a 95% confidence interval from 1.78-8.26, p<0.001. The average age of the NMDA encephalitis group was lower than other encephalitis groups, p < 0.001. Conclusion: Through this study, we observed that the proportion of autoimmune encephalitis was predominant in the encephalitis disease model, with NMDA encephalitis being the most common type of autoimmune encephalitis. There were differences in the monthly incidence rates among different types of encephalitis. Female patients had a higher risk of developing autoimmune encephalitis compared to male patients, and the average age of NMDA encephalitis patients is lower than that of other types of encephalitis.