PHÂN TÍCH CÁC YẾU TỐ TIÊN LƯỢNG TỬ VONG TRÊN BỆNH NHÂN COVID-19 ĐIỀU TRỊ LỌC MÁU HẤP PHỤ TẠI NGHỆ AN

Abstract

Background: Hemodialysis adsorption has been shown to be an effective and safe method of removing cytokines in the treatment of COVID-19 patients. The prognostic factors affecting mortality rate in severe COVID-19 patients need to be assessed. Objectives: To analyze the prognostic factors affecting the treatment results in COVID-19 patients undergoing adsorbent hemodialysis in Nghe An. Research subjects and methods: A cross-sectional descriptive study on 28 COVID-19 patients receiving adsorbent hemodialysis from June 2021 to December 2022 in Nghe An. Results: Our study involving 28 severeCOVID-19 patients receiving adsorbent hemodialysis, showed a high mortality rate of 46.4% (13/28 patients). According to prognostic factors analysis, clinical factors affecting patient treatment outcomes included comorbidities (mortality rate in the comorbidity group is 57.2% compared to 14.3% without comorbidities), hypotension (mortality rate of hypotension group was 75% compared to 25% in the stable blood pressure group), and ventilation at admission (mortality rate in ventilation group was 60% compared to the group without ventilation, it was 12.5%), showing statistically significant differences with p < 0.05. Subclinical factors influencing treatment outcomes included a SOFA (mortality rate in SOFA group ≥ 5 points is 68.8% compared to group < 5 points is 16.7%) and the extent of lung injury on chest X-ray according to total severity score (TSS) (TSS ≥ 7 points has a mortality rate of 66.7% compared to the TSS group < 7 points which is 23.2%), also exhibiting statistically significant differences with p < 0.05. Conclusion: Patients with severe COVID-19 receiving adsorbent hemodialysis had poor prognosis and high mortality rates. Various clinical and paraclinical factors have been analyzed for their impact on treatment outcomes, among which the SOFA score holds value in assessing the severity of COVID-19 patients.