EVALUATING THE VALUE OF THE KYOTO SCALE IN THE DIAGNOSIS OF HELICOBACTER PYLORI INFECTION IN PATIENTS WITH CHRONIC GASTRITIS

Thị Hồng Khanh Đỗ, Thị Việt Anh Phạm

Main Article Content

Abstract

Objective: Evaluate the clinical applicability of the Kyoto scale in diagnosing Helicobacter pylori infection in patients with chronic gastritis. Methods: Cross-sectional descriptive study on 118 patients with chronic gastritis at 19/8 hospital, Ministry of Public Security from August 2022 to June 2023. The patient was indicated for gastroesophageal endoscopy and was evaluated according to the Kyoto scale (mucosal atrophy, intestinal metaplasia, mucosal fold hypertrophy, nodules, diffuse erythema). H. pylori infection is determined by combining Clo - test and histopathology. H. pylori infection is positive in both methods. Results: Among 118 participants, 60/118 (50,8%) were infected with H. pylori. Mild - moderate - severe mucosal atrophy accounts for 34.7%, 25,6%, 2.4%. The rates of intestinal metaplasia, mucosal fold hypertrophy, nodules, and diffuse erythema were 3,4%, 18,6%, 4.6%, 37.3%. Kyoto scores are distributed from 0-4. The Kyoto score has an area under the AUROC curve of 0.87 with p < 0.05, so the Kyoto score is capable of diagnosing H. pylori infection. Choosing a Cutoff score of 2 points, sensitivity 71%, specificity 95.6%, positive predictive value 88%, negative predictive value 77.1% and accuracy 82.7%. Conclusion:The Kyoto score has high accuracy in predicting H. pylori infection in patients with chronic gastritis.

Article Details

References

Hooi JKY, Lai WY, Ng WK, et al. Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis. Gastroenterology. 2017; 153(2):420-429. doi: 10.1053/j.gastro.2017.04.022.
2. Plummer M, Franceschi S, Vignat J, Forman D, de Martel C. Global burden of gastric cancer attributable to Helicobacter pylori. Int J Cancer. 2015;136(2):487-490. doi:10.1002/ijc.28999
3. Mao T, Wang Y, Yin F, et al. Association of Endoscopic Features of Gastric Mucosa with Helicobacter pylori Infection in Chinese Patients. Gastroenterol Res Pract. 2016;2016:6539639. doi:10.1155/2016/6539639
4. Toyoshima O, Nishizawa T, Arita M, et al. Helicobacter pylori infection in subjects negative for high titer serum antibody. World J Gastroenterol. 2018; 24(13):1419-1428. doi:10. 3748/wjg.v24.i13.1419
5. Phạm Hồng Khánh, Vũ Văn Khiên, Trần Thị Huyền Trang (2021) Tần suất và các yếu tố độc lực của Helicobacter pylori ở bệnh nhân viêm dạ dày mạn. Tạp chí Y học Việt Nam.