TÌNH TRẠNG SỬ DỤNG THUỐC KHÁNG ĐÔNG VÀ KẾT CỤC NGẮN HẠN CỦA NGƯỜI BỆNH ĐỘT QUỴ LIÊN QUAN RUNG NHĨ

Abstract

Objectives: To evaluate the status of indications and selection of anticoagulants and to determine the rate of adverse events within 90 days after treatment in patients with cerebral infarction and atrial fibrillation. Methods: Retrospective descriptive study with a sample population of patients with acute cerebral infarction or transient ischemic attack with atrial fibrillation treated as an inpatient at the Department of Neurology, University Medical Center HCMC, Ho Chi Minh City from 01/2018 to 02/2022. Results: Among 277 cases of patients with acute ischemic stroke and atrial fibrillation, the total number of patients who were prescribed OAC at discharge was 227 cases (82.67%). Of these, 13.54% of cases were prescribed vitamin K antagonist (VKA), and 86.46% were prescribed direct oral anticoagulants (DOACs). Rate of adverse events during follow-up: intracranial hemorrhage, gastrointestinal (4.5%); mucosal bleeding (2.7%); embolism - thrombosis (1.83%). Conclusion: The rate of using anticoagulants, especially DOACs, after acute cerebral infarction with atrial fibrillation is common because of their effectiveness and safety