ĐẶC ĐIỂM PHÂN BỐ VÀ KHÁNG KHÁNG SINH CỦA VI KHUẨN ELIZABETHKINGIA MENINGOSEPTICA PHÂN LẬP TẠI BỆNH VIỆN QUÂN Y 103 GIAI ĐOẠN 2014-2022

Abstract

Objectives: determine distribution and antibiotic resistance characteristics of Elizabethkingia meningoseptica isolated at Military Hospital 103 from 2014 to 2022. Subjects and methods: This was a cross-sectional study. The subjects of the study were E. meningoseptica strains isolated at Military Hospital 103 from 2014 to 2022. Results: There were 38 E. meningoseptica strains isolated during the study period. Of which, 60.53% of all strains isolated were in the age group 60 years and older, the highest among other age groups. The rate of E. meningoseptica strains isolated in males (78.95%) was approximately four times higher than that in females (21.05%). E. meningoseptica was most commonly isolated in respiratory specimens (55.26%) and at the ICU (73.68%), no strains were isolated from surgical departments. E. meningoseptica strains were highly resistant (96.3%-100,0%) to most broad-spectrum antibiotics such as ceftazidime, cefepime, imipenem, and meropenem. E. meningoseptica was most susceptible to trimethoprim/ sulfamethoxazole (53.33%), and fluoroquinolones (ciprofloxacin: 32.26%, levofloxacin: 37.93%). Conclusion: E. meningoseptica was highly resistant to most tested antibiotics. This study suggested the need for implementing infection control measures to reduce the antibiotic resistance rate of E. meningoseptica to improving the effectiveness of treatment for patients.