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Date Published: 11/09/2021
Abstract Views: 93
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DOI: https://doi.org/10.51298/vmj.v505i1.1039
Issue
Vol. 505 No. 1 (2021)
Section
Các bài báo
How to Cite
Văn Khiên, V. ., Vũ Nam, Đoàn ., Quang Duật, N. ., Hồng Khánh, P. ., & Thị Huyền Trang, T. . (2021). INITIAL STUDY ON CAGPAI, OIPA, DUPA OF HELICOBACTER PYLORI IN GASTRIC CANCER PATIENTS IN VIETNAM. Vietnam Medical Journal, 505(1). https://doi.org/10.51298/vmj.v505i1.1039

INITIAL STUDY ON CAGPAI, OIPA, DUPA OF HELICOBACTER PYLORI IN GASTRIC CANCER PATIENTS IN VIETNAM

Vũ Văn Khiên1,, Đoàn Vũ Nam2, Nguyễn Quang Duật2, Phạm Hồng Khánh2, Trần Thị Huyền Trang1
1 108 Military Central Hospital
2 Military Hospital 103, Vietnam Military Medical University

Main Article Content

Abstract

Introduction: Since 1994, WHO has classified H.pylori in group I causing gastric cancer. However, the pathogenicity of H. pylori is highly dependent on its virulence factor. Research topic on the rate of cagPAI, oipA, dupA in gastric cancer patients in Vietnam. Patients and mehods: 31 patients with gastric cancer were confirmed on endoscopy and histopathology. CagPAI, oipA, dupA were performed by PCR. Results: Patients ≧ 60 years old accounted for: 64.5%. More men than women: 2.1. Common clinical symptoms: Anorexia (90.3%), dyspepsia (90.3%), epigastric pain (83.9%). Histopathology: Itestinal type accounted for the highest percentage (64.5%). CagPAI, oipA, dupA were positive in gastric cancer patients, respectively: 90.3%, 32.3%, 51.6%. Conclusion: The cagPAI gene of H. pylori is a high risk factor for gastric cancer in Vietnam. Need to study on more quantity

Article Details

Keywords

Helicobacter pylori, gastric cancer, chronic gastritis

References

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