NHẬN XÉT ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH NHÂN VIÊM TUYẾN GIÁP MẠN TÍNH HASHIMOTO

Abstract

Objective: Review of clinical and para-clinical characteristics of patients with chronic Hashimoto's thyroiditis. Research subjects and methods: cross-sectional, retrospective study on a total of 72 patients diagnosed with chronic Hashimoto's thyroiditis according to Leslie J De Groot¹ examination and treatment at the Department of Endocrinology - Diabetes , On-Demand Examination Department of Bach Mai Hospital from January 2008 to September 2012 after excluding patients with: History of thyroid surgery, pregnant women, other types of thyroiditis. Evaluation criteria: thyroid volume², anti-TPO concentration ≥ 34 UI/ml is considered anti-TPO (+) and vice versa, thyroid function³. Results: Hashimoto's chronic thyroiditis is more common in women than in men (87.5% and 12.5%), mainly in the age group of 40-60 (50%); The most common clinical symptom is fatigue (84.7%); The average anti-TPO concentration is 357.3 ± 243.36 UI/ml, the average FT4 concentration is 4.62 ± 4.32 pmol/l, the average TSH concentration is 73.66 ± 36.67 µU /ml. In the group of patients with anti-TPO (+), mainly patients with clinical hypothyroidism (87.5%). There is a negative correlation between TSH, FT4 and thyroid volume; Positive correlation between thyroid volume and FT4. Conclusion: The most common symptom of fatigue is clinical hypothyroidism in patients with positive anti-TPO levels; There is a strong negative correlation between TSH and FT4.