THE CHARACTERISTICS OF PNEUMONIA COMPLICATION IN ADULT MEASLES PATIENTS AT HOSPITAL FOR TROPICAL DISEASES

Triều Lý Võ, Thị Nhất Hạnh Bùi, Hoàng Phi Nguyễn , Đăng Khoa Trần, Minh Nhựt Vương, Thị Hiếu Vũ

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Abstract

Background: About 1/3 of adults with measles develop respiratory complications, including pneumonia which can be fatal or result in unrecoverable sequelae. Objectives: To describe the characteristics of pneumonia in adult measles patients and to determine related factors to pneumonia. Methods: A case series study was conducted in patients aged ≥ 16 years with clinical signs and serological immunoglobulin M test for diagnosis of measles infection resulted in positive. Results: From October 2018 to May 2020, 294 patients meeting the inclusion criteria were enrolled. The average age was 29 ± 6. The sex ratio from male to female was 1:1.06. There were 17 patients with pneumonia in the illness stage and 8 in the convalescence stage. Respiratory failure accounted for 48% of pneumonia patients, and four severe pneumonia patients required ventilator support (16%). Interstitial opacities were the most common abnormality on chest X-rays (8/22 cases). There was an association between patients with chronic diseases and the pneumonia rate (p = 0.04). The majority of patients were treated with antibiotics (85%). Conclusion: Interstitial pneumonia was observed most frequently. Pneumonia requiring respiratory support accounted for a high proportion. The percentage of pneumonia complication in patients with chronic diseases was higher than in those not getting chronic diseases.

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References

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