NGHIÊN CỨU CÁC YẾU TỐ TIÊN LƯỢNG TỬ VONG Ở BỆNH NHI DƯỚI 6 TUỔI BỎNG RẤT NẶNG

Abstract

Objectives: Evaluation of factors predicting mortality in massive burn patients ≤ 6 years old. Subjects and methods: Retrospective study on 288 burn pediatric patients (0-6 years old), burn extent ≥ 30% of total burn surface area (TBSA) treated at the National Burns Hospital from 1/1/2018 to 31/12/ 2022. Patients were divided into two groups of survival and death, and were compared in terms of the characteristics, manifestation and outcome. Results: Mortality rate was 7%. Multivariate analysis showed that the increased deep burn area and hospitalized 24 hours after burn were independently associated with mortality (p < 0,05). increase 1% of a deep burn area increases the risk of death by 0.11 units, hospitalization after 24 hours of burn increases the risk of death by 1.78 units. The prognostic value of mortality in massive burn pediatric patients ≤ 6 years old of deep burn area and hospitalized 24 hours after burn with area under the curve (AUC) is 0.73 and 0.64, respectively. When combining hospitalized 24 hours after burn and deep burn area, the predictive value of mortality increases significantly, at a good level (AUC = 0.84; p < 0.05). The Hosmer - Lemeshow test showed that the regression equation combining hospitalized 24 hours after burn  and deep burn area was consistent with death (ꭓ2 = 8.62; p > 0.05). Conclusion: The increase deep burns area and hospitalized 24 hours after burn increases the risk of death. The mortality prognostic value of hospitalized 24 hours after burn combined with deep burn area were at a good level.