TỶ LỆ ANA DƯƠNG TÍNH TRÊN NGƯỜI KHÁM SỨC KHỎE TỔNG QUÁT TẠI PHÒNG XÉT NGHIỆM SINH HÓA- MIỄN DỊCH - HUYẾT HỌC BẰNG PHƯƠNG PHÁP ELISA, VIỆN PASTEUR TP.HCM 2018-2019

Abstract

Objective: Systemic lupus erymathosus - SLE is the severe disease that affected to their body organs, connective tissues and vascular systems; with its incidence 0,3 - 31,5/100.000; M:F = 10/1 up to every countries. In Vietnam, the SLE health screening by check-up, every years, did not be interested. Methods: The health screening customers who are having their symtoms that met to the 11 clinical indicators up to SLICC-2012 have been recruited; ANA examination performed by ELISA and statistical analysis with Chi-square or Anova (up to its variants). Results: Among 73.218 customers records, there are 128 SLE (+) by clinical check-up (M: F = 33: 95) that have been preliminary diagnosed; (p<0.01). Combining with ANA result by ELISA test, there are 14 ANA (+) cases that have been confirmed; 100% female, account for 10,94% (14/128). It is very interesting within male group what have diagnosed clinical SLE but in laboratory, they have been confirmed negative SLE with ANA (-) (F=221,8 > F crit = 1.96). Conclusion: (SLE) is the rarely diseases and not be attention in communities health check-up. Through this research (2018-2019): there are 0,18% and 0,02% SLE cases have been diagnosis by general examination in clinical and by ELISA ANA test in laboratory, respectively up to SLICC 2012. It is needs to have more long term and deeply scientic researches with all 7 immunological indicators fully for understanding clearly about the SLE situation in the Vietnamese communities.