GIÁ TRỊ CHẨN ĐOÁN CỦA CỘNG HƯỞNG TỪ KHUẾCH TÁN VÀ CỘNG HƯỞNG TỪ TƯƠNG PHẢN ĐỘNG HỌC TRONG PHÂN BIỆT U TUYẾN NƯỚC BỌT MANG TAI LÀNH TÍNH VÀ ÁC TÍNH

Abstract

Purpose: To determine the value of adding diffusion-weighted (DW) magnetic resonance (MR) imaging to dynamic contrastmaterial–enhanced MR imaging when distinguishingbetween benign and malignant parotid tumors. Material and Methods: Theprospective study was conducted on 39 parotid salivary gland tumors with 39 lesions (25 benign, 14 malignant) at the National cancer hospital from June 2020 to June 2021. We evaluated themean ADC, analyze the Time-intensity curve (TIC) of each lesion, determining the value of DWI and DCE in distinguishing benign and malignant parotid tumors. Results: Pleomorphic adenomas have no diffusion restriction on DWI and ADC maps. Malignant neoplasms, Warthin tumors, or lymphomas restricted diffusion. ADC threshold values between pleomorphic adenomas and carcinomas were 1,415 x10^-3 mm²/s with sensitivity and specificity of 72% and 98%, respectively. ADC threshold valueswere 0.905 x 10^-3 mm²/s between Warthin tumors and carcinomas with sensitivity and specificity of 93% and 99%, respectively. On the DCE, when the lesions have a curve of types A and D regarded as benign and there is an overlap when the lesions have a curve of type B and C. The combination of DWI and DCE improves the differentiation between benign and malignant lesions significantly compared with using each method (p < 0.05). Conclusion: Diffuse magnetic resonance with ADC value combined with dynamic contrast magnetic resonance imaging is a useful method for differential diagnosis of common tumors in the parotid glands.