PHÂN BỐ CÁC CHỦNG VI KHUẨN GRAM ÂM THƯỜNG GẶP TẠI BỆNH VIỆN ĐA KHOA TÂM ANH NĂM 2023

Abstract

Gram-negative bacteria play a significant role in infectious diseases, highlighting the importance of understanding their distribution for effective disease surveillance. Methods: This cross-sectional descriptive study aimed to assess the infection rate and prevalence of common gram-negative bacteria at Tam Anh General Hospital in 2023. Results: Among 7196 culture samples analyzed, 1934 tested positive, representing a positivity rate of 26.9%. Respiratory samples exhibited the highest positivity rate at 32.6%, followed by urine (23.2%), blood (5.5%), body fluid (18.0%), and stool (1.5%). A total of 2014 bacterial strains were isolated from positive samples, with Haemophilus influenzae being the predominant strain (44.4%), followed by Moraxella catarrhalis (31.0%) and Escherichia coli (15.9%), with other bacteria collectively accounting for <3.5%. H. influenzae (55.8%) and M. catarrhalis (30.0%) were primary pathogens in respiratory tract infections, while E. coli was the most common strain in the urinary tract (82.5%), blood (77.5%), and body fluid (57.8%). In clinical departments, E. coli predominated in ICU (Intensive care unit) (61.2%), Internal Medicine (56.1%), and Surgery (75.9%), whereas H. influenzae (56.2%) and M. catarrhalis (40.0%) were prevalent in Pediatric department.  Conclusions: The study underscores H. influenzae, M. catarrhalis, and E. coli as leading Gram-negative bacterial pathogens. E. coli notably contributes to sepsis, urinary tract, and body fluid infections, and is pervasive in Internal Medicine, Surgery, and ICU departments, while H. influenzae and M. catarrhalis predominantly affect respiratory ailments and are prevalent in Pediatric departments, emphasizing the importance of vigilant infectious disease monitoring within hospital settings.