EVALUATION OF THE ROLE OF 18FDG-PET/CT IN EVALUATION OF METASTATIC NODES IN PATIENTS WITH NON-SMALL CELL LUNG CANCER INDICATED FOR RADICAL SURGERY
Main Article Content
Abstract
Objective: To study the role of 18FDG-PET/CT in assessing lymph node metastasis in patients with non-small cell lung cancer who are indicated for radical surgery. Subjects and methods: Descriptive prospective study on 82 non-small cell lung cancer patients scheduled for radical surgery at Hanoi Oncology Hospital from April 2022 to March 2023. Results: 75/82 (91.4%) patients had a diagnosis of (+) lymph nodes on 18FDG PET/CT consistent with the pathological diagnosis results after surgery. 18FDG PET/CT diagnosed (+) lymph nodes in the study patient group with a sensitivity of Se = 75%; Specificity 98%; positive predictive value 85.7%, negative predictive value 97%; 96% accuracy.
Article Details
Keywords
Non small cell lung cancer, 18FDG-PET/CT, SUVmax.
References
2. Mai Trọng Khoa (2012), Giá trị của kỹ thuật chụp PET/CT trong đánh giá giai đoạn, tái phát, di căn của UTP KTBN.
3. Mai Trọng Khoa, Trần Hải Bình (2011), Giá trị của PET/CT trong chẩn đoán UTP KTBN, Tạp chí Ung thue học Việt Nam, 2, tr.101-108.
4. Andrea Bille, Ettore Pelosi, Andrea Skanjeti… (2009), Preoperative intrathoracic lymph node staging in patients with NCSLC: accuracy of integrated PET/CT. European J. of cardiothoracic surgery, 36, pp. 440-445.
5. Schmidt-Hansen M, Baldwin D. R, Hasler E… (2014), PET-CT for assessing mediastinal lymph node involvement in patients with suspected resectable non-small cell lung cancer. Cochrane Database of Systematic Reviews, Issue 11. Art. No.: CD009519. DOI: 10.1002/14651858. CD009519.pub2
6. Huseyin Melek, Mehmet Zeki Gunluoglu, Adalet Demir… (2008), Role of positron tomography in mediastinal lymphatic staging of NSCLC. European J. of cardio-thoracic surgery, 33 (2008), pp.294-299.
7. Akram Al Ibraheem, Nader Hirmas, Stefano Fantiet al. (2021), Impact of 18FDG PET/CT, CT and EBUS/TBNA on preoperative mediastinal nodal staging of NSCLC.BMCMedImaging 21:49; https://doi.org/10.1186/s12880 021 00580 w.
8. Gail E. Darling, Donna E. Maziak, Richard I. Inculet (2011), Positron Emission Tomography-Computed Tomography Compared with Invasive Mediastinal staging in Non-small Cell Lung Cancer. J Thorac Oncol.; 6: 1367-1372.