MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ VIÊM PHỔI LIÊN QUAN THỞ MÁY DO ACINETOBACTER BAUMANII ĐA KHÁNG TẠI BỆNH VIỆN ĐA KHOA BẠC LIÊU TỪ NĂM 2023-2024

Abstract

Background: Ventilator-associated pneumonia (VAP) is a type of hospital-acquired pneumonia, especially most common in intensive care units, occurring in mechanically ventilated patients during treatment. Objectives: Describe the characteristics, treatment results and antibiotic resistance of bacteria in patients with VAP caused by multi-drug resistant Acinetobacter baumannii. Research subjects and methods: Cross-sectional descriptive study, clinical intervention without control group in 32 patients with VAP caused by multi-drug resistant A. baumannii at Bac Lieu General Hospital from April 2023 to January 2024. Results: The rate of VAP caused by multi-drug resistant A. baumannii was 37,2%, the average age of patients was 68,6±19,1 years old. Using sedatives and antibiotics before diagnosing pneumonia are the two most common risk factors for VAP caused by A. baumannii. Patients with early VAP had fewer days of mechanical ventilation compared to late VAP (p<0,001). Rate of death, serious illness, return home 68,7%; The rate of recovery and transfer to the clinical deparment is 15,6%. A. baumannii is also 34,4% sensitive to the antibiotic Colistin and 75,0% sensitive to Ampicillin/Sulbactam. Conclusion: VAP caused by multir-drug resistant A.baumanii has a high frequency of morbidity and mortality. With increasing antibiotic resistance, A. baumanii is becoming a burden in intensive care units.